Protein Network Comparative Genomics
نویسندگان
چکیده
منابع مشابه
Comparative Protein Structure Modeling in Genomics
The function of a protein is generally determined by its three-dimensional (3D) structure. Thus, it would be useful to know 3D structure of the thousands of protein sequences that are emerging from the many genome projects. This is the aim of structural genomics. The aim will be achieved by a focused, large-scale determination of protein structures by X-ray crystallography and nuclear magnetic ...
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The detection of gene fusion events across genomes can be used for the prediction of functional associations of proteins, including physical interactions or complex formation. These predictions are obtained by the detection of similarity for pairs of 'component' proteins to 'composite' proteins. Since the amount of composite proteins is limited in nature, we augment this set by creating artific...
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Gene3D http://gene3d.biochem.ucl.ac.uk is a comprehensive database of protein domain assignments for sequences from the major sequence databases. Domains are directly mapped from structures in the CATH database or predicted using a library of representative profile HMMs derived from CATH superfamilies. As previously described, Gene3D integrates many other protein family and function databases. ...
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Stem cell factor (SCF) is a critical protein with key roles in the cell such as hematopoiesis, gametogenesis and melanogenesis. In the present study a comparative analysis on nucleotide sequences of SCF was performed in Humanoids using bioinformatics tools including NCBI-BLAST, MEGA6, and JBrowse. Our analysis of nucleotide sequences to find closely evolved organisms with high similarity by NCB...
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The comparative approach in biology is probably as old as this science itself. Systematic comparative analysis of organisms can be traced at least to the eighteenth century naturalist Carl Linnaeus, who developed the hierarchical classification of plant and animal species on the basis of detailed observations of comparative morphology. The first half of the nineteenth century was marked by outs...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2008
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.22.1_supplement.538.1